An unexpected gift – Children after cancer

Rajasinghe Foundation for Vascular Research and Education:

Today marks the global launch of the United Nations Population Fund’s flagship report ‘State of World Population’.
This year’s report features the story of a resilient Sri Lankan woman and her miracle baby.
We hope Shara’s story will inspire many young women around the world to reach their fullest potential.

SOURCE: unfpa.org/swop-2019 pages 151-152

Sri Lanka: an unexpected gift—children after cancer


Ranasinghe’s early life was tumultuous. Her parents had divorced and the court stipulated that she, a single child, live with her father because he had financial stability and her mother did not.
“My mother was a brilliant child, but she never went beyond secondary school, and she married and had a child by 20,” Shara says.

After her father remarried, Shara suffered at the hands of a stepmother, who beat her at times.

When her own mother asked what had happened, she would make up excuses like she had fallen on the stairs, not wanting to stir up more concern and anger. Despite her unhappy childhood, Shara emerged with an independent and resilient spirit. After moving to Malaysia to pursue a university degree, she began to thrive until in her final year of studies she was diagnosed with cancer. She told her boyfriend that he really ought to leave her, but he refused, standing by her side through gruelling rounds of chemotherapy and radiation.

My mother was a brillant child, but she never went beyond secondary school, and she married and had a child by 20.

When it was over, the doctors said there was a low to zero probability that she would ever bear children.

At one point, she had been asked if she wanted to preserve her eggs, but the subject came up in front of her father and felt too uncomfortable for discussion.

She and her boyfriend decided to marry anyway, and soon after she found she was pregnant. “The stick turning positive was the best thing that ever happened in my life,” she confides Two more children have followed since then, and Shara has moved to Australia to pursue advanced degrees, aiming for a doctorate in communications with cancer patients. While she always wanted many offspring, each pregnancy poses some risk to her fragile health.

Financially, too, three feels like the right number. While Australia has subsidized childcare, she and her husband have worried about being away from their small children and juggled their work so that one parent could always be home with them.

At one point, Shara moved ahead in her teaching career and became the main family breadwinner, while her husband took time off from being an engineer to work flexible hours preparing food in cafes. More recently, his parents have come to live with the couple, and her husband has gone back to engineering.

In the world around her, she sees a growing openness, with women finally moving into leadership positions at her university, and a boy at her daughter’s school who has, for the first time, asked to be treated as a girl. Her first “miracle” daughter is now approaching 10, a talented, sensitive child. “I want her to be very strong,” Shara says.

“I hope she does not encounter discrimination, but there are still so many inequalities.”

She counts Australia as further ahead in understanding a changing world, compared to Sri Lanka, where she says the majority of people retain deeply conservative expectations of women. She enjoys the staunch support of her parents in making choices to pursue her dreams. But, she says, “my country has a few more years to go. I am hopeful that future generations will be born into a Sri Lanka that fosters equal opportunities for all.”

#SWOP19, #ICPD25, #UnfinishedBusiness

UNFPA | UNFPA Asia and the Pacific | United Nations Sri Lanka | United Nations

Launching state of the art Philips Veradius Unity mobile imaging and Excimer Laser for treatment of threatened limbs

The Vascular Group of Naples Office Based Lab (OBL) launches state of the art Philips Veradius Unity mobile imaging and Excimer Laser for treatment of threatened limbs.
With over 17 years of vascular and endovascular surgery experience, we are extending complex therapies into the office outpatient setting to allow for increased safety, faster recovery, and higher satisfaction!

Philips Veradius Unity mobile imaging and Excimer Laser for treatment of threatened-limbs vascular surgery

 

Proud to share our educational support of the next generation of medical students

Rajasinghe Foundation for Vascular Research and Education Foundarion proud to support the next generation of physicians through scholarships at Duke University School of Medicine.

Here is a testimonial we would like to share

“My name is Christopher Calixte and I want personally thank you for the Rajasinghe Vascular Research scholarship I received recently. This means a lot to me especially considering my humble upbringing. I was born in Flatbush, Brooklyn that was riddled with crime and socioeconomic distress. Thankfully I have two loving parents whom are immigrants from Haiti that always reminded that my education should be my top priority. Though education always came first I balanced it with sports all the way through high school.”

 

Letter-Christopher

 

We are very happy to provide this kind of impact by bringing educational support to the next generation of medical students.

Help to change lives for the better, forever! Support Rally For Littles

Big Brothers Big Sisters of the Sun Coast – Rally for Littles is an event that will take place this December 15th, 2018.

Big Brothers Big Sisters of the Sun Coast holds itself accountable for children in its program to achieve measurable outcomes, such as educational success; avoidance of risky behaviors; and higher aspirations, greater confidence and better relationships. The organization provides children facing adversity, often those of single or low-income households or families with strong and enduring, professionally supported one-to-one mentoring relationships that change their lives for the better, forever.

 

You can help by voting (with a donation) for your favorite car.

The order of cars in the rally will be determined by your donations.

Dr. Hiranya Rajasinghe will be driving car number 113. A magnificent Grey Ferrari 488 GTB.

You can support his car by making your donation on this link:

https://one.bidpal.net/rally4littles/browse/donation(details:item/15)

Come out for a great day of food, exotic cars, silent auction and prizes at our Rally For Littles.

Announcing The Manora Elizabeth Panthiage Jayatilleke Fund at Yale University

In memory of Manora Elizabeth Jayatilleke, 1942 – 2018

1942 – 2018, Mrs. Manora Elizabeth Jayatilleke

 

The Rajasinghe Vascular Research and Education Foundation announces the establishment of the Manora Elizabeth Panthiage Jayatilleke Fund at Yale University to help support undergraduate science research particularly for disadvantaged minorities and women as part of the STARS Fellowship Program.

You can check more abouth the program here: https://science.yalecollege.yale.edu/stars

Manora Elizabeth Jayatilleke was a career woman scientist, mentor, and loving mother.

She earned her Bachelor of Science degree at University of Ceylon, Colombo (Sri Lanka) and Masters in Science at Columbia University, New York City (USA).

Her research focused on the biochemistry of liver and alcohol disease at the Bronx VA Hospital, Mount Sinai School of Medicine for over 25 years. She is survived by her three children Arundathi Jayatilleke MD, Ruwan Jayatilleke, and Hiranya A. Rajasinghe MD who are the donors of the endowed fellowship.

Abdominal Aortic Aneurysm Treatment & Medical Management

What is Abdominal Aortic Aneurysm?

“When we talk about Abdominal Aortic Aneurysm Treatment, try to picture the lower part of your aorta getting bigger and bigger. It if grows too much, then the risk of a rupture increases, and the level of danger is higher.

Your life could be in danger and measures need to be taken.

Professional measures in this case, as in any medical case.

An aneurysm takes place when plaques build up inside artery walls. With age these plaques appear more often, affecting the levels of oxygenated blood that are transported to every single part of your body.

Signs and Symptoms

An aneurysm can grow at a very slow rate, without showing any signs over time. Most are spotted on a checkout with your trusted health professional.

If there is a problem, then you will experience any or several these symptoms:

  • A sharp pain in your chest, abdomen or lower back. This uncomfortable sensation can lasts several hours or days. The pain could span through buttocks or legs.
  • A toe turns black or, maybe, blue.
  • You notice your skin is kind of sweaty
  • You start to feel dizzy or weak
  • Your heart rate increases dramatically
  • Vomit

 

Diagnosis

As in everything related with health, the sooner a diagnosis is done, the better.

The Vascular Group of Naples is an institution that advocates for the use of the best technology available.

These are some of the terms you will find more often:

  • Angiogram: this is the most used term in the field when it comes to diagnose an aneurysm. During an X-Ray procedure, blood clots are exposed thanks to a catheter.
  • Abdominal Ultrasound: This procedure allows the physician to have a clear “picture”, thanks to sound waves that go through body tissue located in the abdomen.
  • CT Scan: Here, a bigger picture is taken, in the sense that images are created not only of the abdomen, as with the Abdominal Ultrasound, but the aorta, heart and blood vessels.
  • MRI (Magnetic Resonance Imaging): This is a big piece of equipment, a magnet to be more precise. Computerized images of heart and vessels are created in a very detailed way.

 

Causes

Most of the causes are related with one thing: your lifestyle.

To be more specific, you avoid it by having a healthy lifestyle.

Chances of suffering an Aneurysm are higher if you are overweight, if your diet includes foods with high presence of fat or if you smoke on a regular basis.

There are also other causes that are not under your control like infections on the aorta or high blood pressure.

Risk Factors

Other risk factors that are out of your control are:

  • If you are over 65 years old.
  • Men have a higher propensity to suffer an abdominal aneurysm.
  • Genes play a role here as well, if there is history in your family, there are a chances of having an aneurysm at a younger age.

Prevention

Even there are some factors that you cannot control directly, there are activities that can help you prevent an aneurysm, and most diseases, just by using a daily discipline:

  • Heart health: stay away from cigarettes. In general, avoid smoking.
  • Medication: if you have being diagnosed and are require taking your medication, try to follow your physician instructions as much as you can.
  • Screening test: to be more certain, scheduled an ultrasound with your physician. It helps to spot any kind of problem right away.

 

Initial Management

Going into more detail, if you are diagnose, this is an overview of how the procedure will be:

– Prehospital care

As with any health procedure, paying attention to details is critical.

You can visualize prehospital care as follows:

  • Breathing is highly important, that is why our professionals makes sure that you don´t have any problem by maintaining a proper oxygenation all the time.
  • The physician in charge may ask some question to know more about the history of the patient.
  • As in any hospital procedure, the patient vital signs will be monitored upon arrival or while on route to the hospital in an ambulance.
  • The physician must pay attention to any symptom that might indicate that the patient could suffer a shock during the intervention.

 

– Emergency department care

When conditions mandate that the patient needs surgical intervention, all the equipment and procedures are set up to deal with things like: hemorrhagic shock, which are dealt with blood transfusions and surgery.

The clinicians must be aware of sudden changes in blood pressure.

Options for Surgical Intervention

Over the last 50 years there have been 2 established procedures:

–          Open Repair

Open repair of AAA has a survival rate of 96%. Cardiac risk is reduced thanks to constant cardiac investigations and beta blockade.

Laboratory assessment is one of the first steps that need to be performed as well as a careful examination of the patient history and amplification on some details the clinician might consider of high importance.

Patient current lifestyle needs to be carefully examined to spot possible mental and physical deterioration.

All risk factors are listed and taken in consideration.

–          Endovascular Repair

Also known as EVAR, has become, over the last 30 years, into a wide alternative to Open Repair.

Its minimal invasive techniques and lower preoperative risks made this one of the most used procedures. It has extended, even to elder population.

EVAR consist in accessing the abdominal aorta via small incisions over the femoral vessels.

An endograft is placed within the lumen of the AAA.

Think of these grafts as protection that decreases the pressure of the walls. This way, the risk of aortic rupture is lowered.

Consultations

The support of a radiologist is mandatory to determine if ultrasonography or Magnetic Resonance Imaging.

If the abdominal aorta exceeds a diameter of 3 cm there must be a follow-up with a vascular surgeon.

Over 4 cm a surgical repair is the best approach.

As in any surgery, anesthesia is required along with the necessary personnel to perform a successful surgery.

All professional health assessment needs to be done with precision and quality standards must be followed.

Complications

If it is too late and the AAA is not diagnosed, these problems may arise:

  • Rupture: there is only a 20% survival rate in an emergency situation. Remember that the aorta supplies most of the blood to the body. That´s why is so critical.
  • Blood clots: that bloods flows through the body without any restriction is vital. That´s why a block on any blood vessel can cause troubles.

 

Aneurysm Terminology

Aneurysm Definition: for adult patients, a diameter bigger than 3 cm, is considered aneurysmal.

Less than 4.0 cm, we talk about small aneurysms.

Between 4.0 cm and 5.5 cm we talk about medium aneurysms.

Larger than 5.5 cm, are called larger aneurysms.

An expansion larger than 5.0 cm in a period of 6 months increases the risks.

Aneurysm Repair

Elective AAA repair is not recommended until the risk of rupture exceeds the risks associated with repair. This is a critical point where professional decisions are needed.

Other factors are very important to be considered: the presence of a coexistent peripheral artery disease. Diseases such as: iliac aneurysm and femoral aneurysm.

Observations are key when talking about conservative management. These procedures include clinical evaluation and AAA surveillance

Medical Risk Assessment

As physicians, we look for perioperative complications such as: coronary ischemia, arrhythmias or pneumonia.

Patients with smoking history need a closer observation, since the risk factors are more much higher and there are correlated with other diseases.

Conservative Management

As an accepted rule, AAA smaller than 5.5 cm need to be managed in a more conservative way.

Potentially Beneficial Therapies:

  • Stop smoking: aneurysm is a word with high chances of being mentioned on a regular smoker record.

It is on the patient´s will and discipline to control this behavior. More than control it, it is best to eliminate it definitely.

  • Physical activity: a daily physical activity is a must for patients diagnose with AAA, this a fact accepted not only in the medical community but in society in general.

Moderated physical activity is the first step. It is best if these activities are monitored by a health professional. Otherwise, the risks will be others. Moderation is best.

Professional recommendation also applies for a proper diet.

Statistics

In the paper “Epidemiology of Aortic Aneurysm Repair in the United States from 1993 to 2003”, it is stated that AAA has been described in the medical community over the last 50 years.

To spot trends in mortality, samples were taken between 1993 and 2003 in the United States.

These are their results:

“Overall rates of treated unruptured and ruptured AAAs remained stable (unruptured 12 to 15/100,000; ruptured 1 to 3/100,000). In 2003, 42.7% of unruptured and 8.8% of ruptured AAAs were repaired through an endovascular approach. Inhospital mortality following unruptured AAA repair continues to decline for open repair (5.3% to 4.7%, P = 0.007).

Mortality after elective endovascular AAA repair also has statistically decreased (2.1% to 1.0%, P =0.024) and remains lower than open repair.

Mortality rates for ruptured AAAs following repair remain high (open: 46.5% to 40.7%, P = 0.01; endovascular: 40.0% to 35.3%, P =0.823).”

This shows certain level of stability for patients treated with elective is Abdominal Aortic Aneurysm, although there is a change in the treatment paradigm where there is a preference for elective endovascular AAA repair.

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